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Wednesday 8 May 2024

Odd vaccine that increases your chances of getting the disease!

A recent paper titled Effectiveness of the 2023-2024 Formulation of the Coronavirus Disease 2019 mRNA Vaccine against the JN.1 Variant analysed data on the efficacy of mRNA vaccines againstCOVID-19 in a cohort of health workers at the Cleveland clinic. The paper has been published in preprint format inviting peer review.

The analysis comes to a daunting conclusion, that the more vaccine jabs one receives the greater the chances of contracting COVID-19.

Please read the paper in full, but I have reproduced the Abstract below;-
The purpose of this study was to evaluate whether the 2023-2024 formulation of the COVID-19 mRNA vaccine protects against COVID-19 caused by the JN.1 lineage of SARS-CoV-2.
Employees of Cleveland Clinic in employment when the JN.1 lineage of SARSCoV2 became the dominant circulating strain, were included. Cumulative incidence of COVID-19 was examined prospectively. Protection provided by vaccination (analyzed as a time-dependent covariate) was evaluated using Cox proportional hazards regression. The analysis was adjusted for the propensity to get tested, age, sex, pandemic phase when the last prior COVID-19 episode occurred, and the number of prior vaccine doses.
Among 47561 employees, COVID-19 occurred in 838 (1.8%) during the 16-week study period. In multivariable analysis, the 2023-2024 formula vaccinated state was associated with a significantly lower risk of COVID-19 while the JN.1 lineage was the dominant circulating strain (hazard ratio [HR], .77; 95% confidence interval [C.I.], .62-.94; P = .01), yielding an estimated vaccine effectiveness of 23% (95% C.I., 6%-38%). Compared to 0 or 1 prior vaccine doses, risk of COVID-19 was incrementally higher with 2 prior doses (HR, .1.46; 95% C.I., 1.12-1.90; P < .005), 3 prior doses (HR, 1.95; 95% C.I., 1.51-2.52; P < .001), and more than 3 prior doses (HR, 2.51; 95% C.I., 1.91-3.31; P < .001).
 The 2023-2024 formula COVID-19 vaccine given to working-aged adults afforded a low level of protection against the JN.1 lineage of SARS-CoV-2, but a higher number of prior vaccine doses was associated with a higher risk of COVID-19. 

These are disturbing results and present a case against vaccination. However, the natural argument would be that being vaccinated may provide protection against the severity of the COVID infection. So even if you are more likely to catch COVID, vaccination will nevertheless protect you against severe illness.

I am looking for a study that looks at the likelihood of severe illness vs vaccine status. Watch this space

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